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Journal of Scientific and Industrial Research (JSIR) >
JSIR Vol.71 [2012] >
JSIR Vol.71(04) [April 2012] >
| Title: | Formulation and development of antipsoriatic herbal gelcream |
| Authors: | Kuchekar, Shantanu
Bhise, Kiran |
| Keywords: | Factorial Design
Gelcream
Myrrh Oil
Psoriasis |
| Issue Date: | Apr-2012 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | This study presents formulation and development
of patient friendly antipsoriatic topical gelcreams using Simulgel NS
and Sepicide HB with Myrrh oil. Optimized formulation F5 depicted that gelcream
had a viscoelastic nature with good creep recovery, and non-Newtonian behavior.
Stability studies for three months at 40± 2oC and 75±5% RH of Formulation F5 showed no change in
colour and consistency, and pH remained between 5.7 and 5.9. Primary skin irritation
test conducted on 30 healthy volunteers demonstrated nonirritating nature of
F5. Thus Simulgel NS and Sepicide HB (conc., 2% w/v each) were
found to give better anti-inflammatory gelcream containing myrrh oil with good
consistency and stability. |
| Page(s): | 279-284 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-1084 (Online); 0022-4456 (Print) |
| Source: | JSIR Vol.71(04) [April 2012]
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