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JSIR Vol.71(04) [April 2012] >


Title: Formulation and development of antipsoriatic herbal gelcream
Authors: Kuchekar, Shantanu
Bhise, Kiran
Keywords: Factorial Design
Gelcream
Myrrh Oil
Psoriasis
Issue Date: Apr-2012
Publisher: NISCAIR-CSIR, India
Abstract: This study presents formulation and development of patient friendly antipsoriatic topical gelcreams using Simulgel NS and Sepicide HB with Myrrh oil. Optimized formulation F5 depicted that gelcream had a viscoelastic nature with good creep recovery, and non-Newtonian behavior. Stability studies for three months at 40± 2oC and 75±5% RH of Formulation F5 showed no change in colour and consistency, and pH remained between 5.7 and 5.9. Primary skin irritation test conducted on 30 healthy volunteers demonstrated nonirritating nature of F5. Thus Simulgel NS and Sepicide HB (conc., 2% w/v each) were found to give better anti-inflammatory gelcream containing myrrh oil with good consistency and stability.
Page(s): 279-284
CC License:  CC Attribution-Noncommercial-No Derivative Works 2.5 India
ISSN: 0975-1084 (Online); 0022-4456 (Print)
Source:JSIR Vol.71(04) [April 2012]

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