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Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.50 [2012] >
IJEB Vol.50(04) [April 2012] >
| Title: | Immunomodulatory effects of alcoholic and hydroalcoholic extracts of Moringa olifera Lam leaves |
| Authors: | Banji, Otilia J F
Banji, David
Kavitha, R |
| Keywords: | Immunomodualtor
Humoral Response
Moringa Olifera
Nutrient
Phagocytic Activity |
| Issue Date: | Apr-2012 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Effects of 50, 100 and 200 mg/kg body weight
of the alcoholic and hydro-alcoholic extract of leaves of M. olifera were studied on various immune paradigms like delayed
type hypersensitivity reaction using SRBC as an antigen, determination of antibody
titer, neutrophil adhesion test as an indicator for neutrophil index, total
leucocyte count in cyclophosphamide induced immunosuppressed animals and carbon
clearance assay as a measure of phagocytic activity. Hydro-alcoholic
extract of M. olifera
substantially enhanced cellular immune response, humoral immune response,
neutrophil index and phagoctic activity in doses of 100 and 200 mg/kg body
weight. The ethanolic extract (200 mg/kg body wieght)
was efficient in improving immune response. The results suggest that M.
olifera has a significant role to
play as an immune stimulator. |
| Page(s): | 270-276 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Source: | IJEB Vol.50(04) [April 2012]
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