Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/13735
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dc.contributor.authorSinha, Mahuya-
dc.contributor.authorDas, Dipesh Kr-
dc.contributor.authorDatta, Sanjukta-
dc.contributor.authorGhosh, Santinath-
dc.contributor.authorDey, Sanjit-
dc.date.accessioned2012-03-16T12:02:54Z-
dc.date.available2012-03-16T12:02:54Z-
dc.date.issued2012-03-
dc.identifier.issn0975-1009 (Online); 0019-5189 (Print)-
dc.identifier.urihttp://hdl.handle.net/123456789/13735-
dc.description209-215en_US
dc.description.abstractProtective effect of Moringa oleifera leaf extract (MoLE) against radiation-induced lipid peroxidation has been investigated. Swiss albino mice, selected from an inbred colony, were administered with MoLE (300 mg/kg body wt) for 15 days before exposing to a single dose of 5 Gy 60Co-gamma radiation. After treatments, animals were necropsied at different post irradiation intervals (days 1, 7 and 15) and hepatic lipid peroxidation and reduced glutathione (GSH) contents were estimated to observe the relative changes due to irradiation and its possible amelioration by MoLE. It was observed that, MoLE treatment restored GSH in liver and prevented radiation induced augmentation in hepatic lipid peroxidation. Phytochemical analysis showed that MoLE possess various phytochemicals such as ascorbic acid, phenolics (catechin, epicatechin, ferulic acid, ellagic acid, myricetin) etc., which may play the key role in prevention of hepatic lipid peroxidation by scavenging radiation induced free radicals.en_US
dc.language.isoen_USen_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJEB Vol.50(03) [March 2012]en_US
dc.subjectGamma Radiationen_US
dc.subjectLipid Peroxidationen_US
dc.subjectLiveren_US
dc.subjectReactive Oxygen Speciesen_US
dc.titleAmelioration of ionizing radiation induced lipid peroxidation in mouse liver by Moringa oleifera Lam. leaf extracten_US
dc.typeArticleen_US
Appears in Collections:IJEB Vol.50(03) [March 2012]

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