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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Bharatiya Vaigyanik evam Audyogik Anusandhan Patrika (BVAAP) >
BVAAP Vol.19 [2011] >
BVAAP Vol.19(2) [December 2011] >
| Title: | Anti-inflammatory, analgesic and antioxidant potential of the stem bark of Amra (Spondias mangifera Willd.) |
| Authors: | Sachan, Nikhil K
Arif, Muhammad
Zaman, M K
Kumar, Yatindra |
| Issue Date: | Dec-2011 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | The anti-inflammatory and analgesic activities of ethyl acetate
(EAFSM) and n-butanol (NBFSM) fractions of alcoholic extract of S. mangifera
bark
were evaluated by using carrageenan induced rat paw edema and by tail-flick
method in rats. The radical scavenging activity of ethanolic extract, aqueous
extract and fractions was determined by using DPPH radical scavenging capacity
assay. Two fractions of the alcoholic extract, EAFSM and NBFSM at the dose of
75, 150 & 300 mg/kg b.w. orally after overnight fasting, showed significant
reduction in paw volume when compared with respective control group of
carrageenan challenge. Different doses of extract fractions also showed
significant prolongation of tail-flick latency of rat (P<0.01). Different
concentrations of alcoholic, aqueous extracts and fractions of alcoholic
extract showed significant free radical scavenging capacity against DPPH
generated free radicals. |
| Page(s): | 211-218 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-2412 (Online); 0771-7706 (Print) |
| Source: | BVAAP Vol.19(2) [December 2011]
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