NISCAIR Online Periodicals Repository

NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR)  >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.50 [2012] >
IJEB Vol.50(02) [February 2012] >


Title: Cold stress interaction on organophosphate insecticide poisoning: Age-related assessment in rat cerebral cortex
Authors: Poojary, Annappa
Basha, P Mahaboob
Keywords: Cerebral Cortex Enzymes
Chlorpyrifos
Cold Stress
Issue Date: Feb-2012
Publisher: NISCAIR-CSIR, India
Abstract: The present study was undertaken to identify the nature of the interactive effects of chlorpyrifos (CPF) and cold stress (15° and 20°C) on the activities of acetyl cholinesterase (AChE), choline acetyl transferase (ChAT), Na+, K+-ATPase and malondialdehyde (MDA) level in the cerebral cortex of 1 week, 3 weeks and 3 months of age. The results indicated an interaction of CPF with age of animal and cold exposure resulting in marked decrease in the activity levels of AChE, ChAT, Na+, K+-ATPase, followed by increased MDA levels. Overall, the effects of co-exposure of cold stress and CPF were appreciably different from either of the exposures. However, synergistic-action of CPF and cold stress at 15°C showed a greater inhibition of AChE, ChAT, and Na+, K+-ATPase in comparison with CPF or cold stress alone and together at 20°C. The results reveal that young animals are markedly more sensitive to interactive effects of CPF and cold stress than adults.
Page(s): 110-116
CC License:  CC Attribution-Noncommercial-No Derivative Works 2.5 India
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Source:IJEB Vol.50(02) [February 2012]

Files in This Item:

File Description SizeFormat
IJEB 50(2) 110-116.pdf105.74 kBAdobe PDFView/Open
 Current Page Visits: 539 
Recommend this item

 

National Knowledge Resources Consortium |  NISCAIR Website |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2012 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 620499 since 06-Feb-2009  Last updated on 13-Nov-2014Webmaster: nopr@niscair.res.in