Please use this identifier to cite or link to this item:
Title: Synthesis and biological evaluation of some novel 2-mercaptobenzothiazoles carrying 2-pyrazoline
Authors: Azam, Md. Afzal
Suresh, Bhojraj
Keywords: Anti-inflammatory Activity
Antimicrobial Activity
Ulcerogenic Action
Issue Date: Feb-2012
Publisher: NISCAIR-CSIR, India
Abstract: This study presents synthesis of several 2-mercaptobenzothiazole derivatives 6a-s bearing 2-pyrazoline at the second position. Compounds 6h, 6i, 6j and 6n exhibited significant antimicrobial activity (inhibition zone 30-35 mm) against Pseudomonas aeruginosa. Compounds 6i, 6j and 6n showed significant analgesic and anti-inflammatory activities. Compounds 6i and 6n showed significant gastrointestinal protection compared to the standard drug diclofenac sodium.
Description: 113-119
ISSN: 0975-1084 (Online); 0022-4456 (Print)
Appears in Collections:JSIR Vol.71(02) [February 2012]

Files in This Item:
File Description SizeFormat 
JSIR 71(2) 113-119.pdf35.83 kBAdobe PDFView/Open

Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.