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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.51B [2012] >
IJC-B Vol.51B(01) [January 2012] >
| Title: | Microwave assisted synthesis and antibacterial properties of some new 2-alkyl/aryl-(6-substitutedcoumarin-3-yl)imidazo[2,1-b][1,3,4]thiadiazoles |
| Authors: | Jakhar, Anshu
Makrandi, J K |
| Keywords: | Microwave irradiation
2-alkyl/aryl-(6-substitutedcoumarin-3-yl)imidazo [2,1-b][1,3,4]thiadiazoles
3-(2-bromoacetyl)-6-substitutedcoumarins
5-alkyl/aryl-2-amino-1,3,4-thiadiazoles
Antibacterial properties |
| Issue Date: | Jan-2012 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | A series of
2-alkyl/aryl-(6-substitutedcoumarin-3-yl)imidazo[2,1-b][1,3,4] thiadiazoles 3a-o
have been synthesized by reacting 3-(2-bromoacetyl)-6-substitutedcoumarins 1 with various
5-alkyl/aryl-2-amino-1,3,4-thiadiazoles 2
under normal thermal condition as well as microwave irradiation. The latter
condition is found to be much more efficient in terms of time and yield. The
structures of the newly synthesized compounds have been characterized by
elemental analysis, IR and 1H NMR spectral data. All the newly
synthesized compounds have been tested for their antibacterial properties
against gram-positive and gram-negative bacteria. |
| Page(s): | 291-296 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.51B(01) [January 2012]
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