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Title: Iodine catalyzed protection of -hydroxy acids and its application for the synthesis of -hydroxy lactone
Authors: Sharma, Chinta Mani
Kashyap, Bishwapran
Phukan, Prodeep
Keywords: Protection;-hydroxy acid;Iodine;Catalyst;Cyclohexanone
Issue Date: Jan-2012
Publisher: NISCAIR-CSIR, India
Abstract: Iodine has been found to be an effective catalyst for protection of -hydroxy acids under mild reaction conditions. Various -hydroxy acids could be protected using cyclohexanone derivatives in high yield in presence of a catalytic amount of iodine at room temperature. This method has further been extended for the synthesis of -hydroxy lactone from l-(+)-malic acid.
Page(s): 323-327
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.51B(01) [January 2012]

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