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Title: Molecular iodine mediated one step synthesis and antibacterial properties of some 3-aryl-6-(6-substituted-4-methylcinnolin-3-yl)-7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines
Authors: Jakhar, Anshu
Makrandi, J K
Keywords: 6-(6-Substituted-4-methylcinnolin-3-yl)-7H-1,2,4-triazolo[3,4-b][1,3,4] thiadiazines
molecular iodine
Issue Date: Jan-2012
Publisher: NISCAIR-CSIR, India
Abstract: 3-Aryl-6-(6-substituted-4-methylcinnolin-3-yl)-7H-1,2,4-tria¬≠zolo[3,4-b][1,3,4]thiadiazines 3a-l have been synthesized directly in one step by iodine mediated condensation of 3-acetyl-6-substituted-4-methylcinnoline 1 with 3-aryl-4-amino-5-mercapto-1,2,4-triazoles 2. These compounds have been found to possess very good antibacterial activity at 10 ppm.
Description: 313-317
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.51B(01) [January 2012]

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