NISCAIR Online Periodicals Repository

Research Journals >
Indian Journal of Natural Products and Resources (IJNPR)
[Formerly Natural Product Radiance (NPR)]
IJNPR Vol.2 [2011] >
IJNPR Vol.2(4) [December 2011] >

Title: Molluscicidal and ovicidal activity of euphorginol against two harmful freshwater gastropods
Authors: Chauhan, Saroj
Singh, Ajay
Keywords: Euphorbia tirucalli
Indoplanorbis exustus
Lymnaea acuminata
Issue Date: Dec-2011
Publisher: NISCAIR-CSIR, India
IPC CodeInt. cl. (2011.01)—A61K 36/47, A61K 129/00, A01P 9/00
Abstract: Two freshwater gastropods Lymnaea acuminata and Indoplanorbis exustus are the intermediate host of Fasciola hepatica, which causes endemic fascioliasis disease in cattle and livestock and thus cause immense harm to man and domestic animals in northern part of India. Thousands of the chemicals used for controlling these snails cause serious environmental pollution. The present investigation deals with molluscicidal potential of active compound euphorginol isolated from the stem bark of a plant Euphorbia tirucalli Linn. against the above harmful freshwater snails in laboratory as well as in pond. The toxicity of euphorginol was time as well as dose dependent and there was a significant negative correlation between LC values and exposure periods. Thus, the LC50 values of euphorginol was decreased from 1.64 mg/l (24h) >1.32 mg/l (48h) >0.71 mg/l (72h) >0.46 mg/l (96h) in case of L. acuminata and from 1.91 mg/l (24h) >1.78 mg/l (48h) >0.88 mg/l (72h) >0.56 mg/l (96h) in the case of I. exustus in laboratory. Similar pattern of toxicity of euphorginol was found in the pond against both the snails but toxicity of euphorginol was reduced about four times in pond than laboratory. The sub lethal doses (20% and 40% of 24h LC50) of euphorginol were exposed to the eggs of both snails and effect was observed up to 28 days to assess its ovicidal activity under laboratory condition. It was observed that sub lethal doses of euphorginol significantly reduced the hatchability of both the snails and maximum reduction was found at the higher doses. It also reduced the survivability of hatchlings to zero percent in the case of L. acuminata only after 21 days of hatching than control group. The LC90 (24h) doses of euphorginol against snails have no apparent killing in non target organism i.e. fish Channa puctatus in the treatment of mixed population of snails and fish which shares the habitat of these snails. Thus, the active compound euphorginol is toxic against both the snails and can be helpful in management of fascioliasis eco-friendly.
Page(s): 452-457
CC License:  CC Attribution-Noncommercial-No Derivative Works 2.5 India
ISSN: 0976-0512 (Online); 0976-0504 (Print)
Source:IJNPR Vol.2(4) [December 2011]

Files in This Item:

File Description SizeFormat
IJNPR 2(4) 452-457.pdf118.42 kBAdobe PDFView/Open
 Current Page Visits: 682 
Recommend this item


Online Submission of Articles |  NISCAIR Website |  National Knowledge Resources Consortium |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2015 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 168702 since 01-Sep-2015  Last updated on 29-Jun-2016Webmaster: