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Title: Effect of solvents on total phenolics, antioxidant and antimicrobial properties of Bridelia retusa Spreng. stem bark
Authors: Tatiya, Anil U
Tapadiya, Ganesh G
Kotecha, Sneha
Surana, Sanjay J
Keywords: Antibacterial;Antioxidant;Bridelia retusa;Polyphenolic content
Issue Date: Dec-2011
Publisher: NISCAIR-CSIR, India
IPC Code: Int. cl. (2011.01)—A61K 36/00
Abstract: Effect of different solvents such as water, ethanol (50%), methanol (50%) and acetone (70%) on the total polyphenol content, antioxidant and antimicrobial activities of stem bark of B. retusa Spreng. was studied. Phenolic content of extracts were determined using Folin-Ciocalteu assays and antioxidant activity was carried out by DPPH and reducing power assay. The results showed that different solvent with different polarity possess significant effect on polyphenolic contents and antioxidant activity. Acetone extract shown highest polyphenol content, 4.7-7.6 mg equivalent to Gallic acid. It also has shown highest antioxidant activity. MIC value <5mg/ml indicated that stem bark of this plant is a potential natural antimicrobial agent.
Page(s): 442-447
ISSN: 0976-0512 (Online); 0976-0504 (Print)
Appears in Collections:IJNPR Vol.2(4) [December 2011]

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