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Research Journals >
Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.50 [2012] >
IJEB Vol.50(01) [January 2012] >
| Title: | Effect of Alternanthera brasiliana (L) Kuntze on healing of dermal burn wound |
| Authors: | Barua, Chandana C Talukdar, Archana Begum, Shameem A Buragohain, Bhaben Roy, Jayanti Datta Pathak, Debesh C Sarma, Dilip K Gupta, Asheesh K Bora, Rumi S |
| Keywords: | Alternanthera brasiliana Antioxidants Collagen Experimental burn Wound healing |
| Issue Date: | Jan-2012 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Wound healing
activity of methanol extract of Alternanthera
brasiliana [5% (w/w) ointment] was evaluated
in experimental burn wound model in rats. Healing potential
was assessed by the rate of wound contraction, estimation of anti-oxidants like
catalase, superoxide dismutase, reduced glutathione, protein, vitamin C and
hydroxyproline, along with histopathological examination on 8th day
post wounding. The
statistical data indicated that there was significant increase in wound contraction along with augmented
level of antioxidants in granulation tissues in A.
brasiliana treated group. Histopathological assessment of the
granulation tissue revealed formation of epidermis with keratin layer and
deposition
of collagen fibers after treatment
with the plant extract.
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| Page(s): | 56-60 |
| CC License: | CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Source: | IJEB Vol.50(01) [January 2012]
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