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Title: Synthesis of thiazolyl benzimidazoles and thiazolyl coumarins linked to isoxazole as possible biodynamic agents
Authors: Rajanarendar, E
Murthy, K Rama
Reddy, M Nagi
Shaik, Firoz Pasha
Keywords: Cyclocondensation;Isoxazolyl thiazolyl-5-acetic acids;Benzimidazolyl isoxazolyl thiazolan-4-ones;Chromenyl isoxazolyl thiazolan-4-ones
Issue Date: Nov-2011
Publisher: NISCAIR-CSIR, India
Abstract: A new series of linked heterocyclics, 5-(1H-benzo[d]imidazol-2-yl-methyl)-3-(3-methyl-5-[(E)-2-phenyl-1-ethenyl]-4-iso­xazol­yl)-2-aryl-1,3-thiazolan-4-ones 4 and 3-{3-methyl-5-[(E)-2-phenyl-1-ethenyl]-4-isoxazolyl}-5-(2-oxo-2H-3-chromenyl)-2-ar­yl-1,3-thiazolan-4-ones 5 have been synthesized by the cyclo­condensation of 4-benzalamino-3-methyl-5-styrylisoxazole 2 with mercapto succinic acid followed by cyclization with 1,2-phenylenediamines or salicylaldehydes. Structures of all the newly synthesized compounds 3-5 have been confirmed by spectral and micro analytical data.
Page(s): 1658-1666
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.50B(11) [November 2011]

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