Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/13047
Title: Ecofriendly and sustainable efficient synthesis of bis(indolyl)methanes based on recyclable Brønsted (CSA) or Lewis (ZrOCl<sub>2</sub>.8H<sub>2</sub>O) acid catalysts
Authors: Mishra, Sarita
Ghosh, Rina
Keywords: ZrOCl<sub>2</sub>.8H<sub>2</sub>O
CSA
Bis(indolyl)methane
Indole
Issue Date: Nov-2011
Publisher: NISCAIR-CSIR, India
Abstract: A simple, highly efficient, environmentally benign synthesis of bis(indolyl)methanes and bis(indolyl)glycoconjugate by electrophilic substitution reaction of indole or methylindoles with a variety of aldehydes or simple ketones catalysed by 5 mol% of camphor sulphonic acid (CSA) or zirconium oxychloride octahydrate (ZrOCl<sub>2</sub>.8H<sub>2</sub>O) in aqueous medium (20% EtOH-H<sub>2</sub>O) at ambient temperature is reported. The reactions also proceed efficiently with recovered catalyst (CSA or ZrOCl<sub>2</sub>.8H<sub>2</sub>O) and under scale-up condition.
Description: 1630-1636
URI: http://hdl.handle.net/123456789/13047
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.50B(11) [November 2011]

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