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IJC-B Vol.50B(11) [November 2011] >


Title: Synthesis and cytotoxity of novel benzopyran derivatives
Authors: Tripathi, Anil K
Mukherjee, Debaraj
Koul, Surrinder
Taneja, Subhash C
Agrawal, Satyam K
Sharma, Parduman R
Saxena, Ajit K
Keywords: Acetophenones
Chromanone
Benzopyrans
Cytotoxic
Anti-hypertensive
Issue Date: Nov-2011
Publisher: NISCAIR-CSIR, India
Abstract: In-vitro cytotoxic activity of benzopyrones and benzopyran derivatives has been evaluated against a panel of several human cancer cell lines. Out of 16 compounds prepared and screened, four compounds have shown significant cytotoxicity against human breast, liver, colon and prostrate cancer cell lines. Apoptosis rather than necrosis has been established as the mode of mechanism for the cytotoxicity of the studied molecules using Light Microscopic and Scanning Electron Microscopic techniques.
Page(s): 1619-1629
CC License:  CC Attribution-Noncommercial-No Derivative Works 2.5 India
ISSN: 0975-0983(Online); 0376-4699(Print)
Source:IJC-B Vol.50B(11) [November 2011]

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