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IJEB Vol.49(11) [November 2011] >


Title: Cancer stem cell markers as potential targets for epithelial cancers
Authors: Madka, Venkateshwar
Rao, Chinthalapally V
Keywords: Cancer stem cells
CD133
DCAMKL-1
LGR5
Mushahi-1
Tumor initiating cells
Issue Date: Nov-2011
Publisher: NISCAIR-CSIR, India
Abstract: In recent years, the role of tumor-initiating cells (popularly known as cancer stem cells) in tumor development and availability of novel cancer stem cell/tumor initiating cell markers promises a new arena in understanding their role in developing novel targeted molecules. It is important to identify and understand the relevance of cancer stem cells (CSC)/tumor initiating cells (TIC) in tumor development and to design appropriate strategies for CSCs and TICs elimination, which is crucial to future cancer prevention and treatment. In this review, we attempt to define various potential markers of cancer stem cells and potential exploration as therapeutic targets for epithelial cancer prevention and treatment.
Page(s): 826-835
CC License:  CC Attribution-Noncommercial-No Derivative Works 2.5 India
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Source:IJEB Vol.49(11) [November 2011]

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