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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.50B [2011] >
IJC-B Vol.50B(10) [October 2011] >
| Title: | Synthesis, characterization and antibacterial activity of benzimidazole derivatives carrying quinoline moiety |
| Authors: | Gowda, Janardhana
Khader, A M A
Kalluraya, Balakrishna
Hidayathulla, Syed |
| Keywords: | Benzimidazoles
Quinolines
2-(1H-benzimidazol-2-yl)thieno[2,3-]quinoline
Antibacterial activity |
| Issue Date: | Oct-2011 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | A new series 2-(1H-benzimidazol-2-yl)-6-substitutedthieno[2,3-b]quinolines
4 have been synthesized by a
one-step process in which 2-(chloromethyl)-1H-benzimidazole 2/2-(mercaptomethyl)-1H-benzimidazoles
6 undergo nucleophilic substitution
and cyclisation with 2-mercaptoquinoline-3-carbaldehyde 1/2-chloroquinoline-3-carbaldehyde 5. The compounds have
been synthesized by two methods to select a method of higher yield. The newly
synthesized compounds have been characterized by IR, CHNS analysis, LC-MS and 1H
NMR and also screened for antibacterial activity. |
| Page(s): | 1491-1495 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.50B(10) [October 2011]
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