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http://nopr.niscair.res.in/handle/123456789/12852
Title: | Synthesis, characterization and antibacterial activity of benzimidazole derivatives carrying quinoline moiety |
Authors: | Gowda, Janardhana Khader, A M A Kalluraya, Balakrishna Hidayathulla, Syed |
Keywords: | Benzimidazoles;Quinolines;2-(1H-benzimidazol-2-yl)thieno[2,3-]quinoline;Antibacterial activity |
Issue Date: | Oct-2011 |
Publisher: | NISCAIR-CSIR, India |
Abstract: | A new series 2-(1H-benzimidazol-2-yl)-6-substitutedthieno[2,3-b]quinolines 4 have been synthesized by a one-step process in which 2-(chloromethyl)-1H-benzimidazole 2/2-(mercaptomethyl)-1H-benzimidazoles 6 undergo nucleophilic substitution and cyclisation with 2-mercaptoquinoline-3-carbaldehyde 1/2-chloroquinoline-3-carbaldehyde 5. The compounds have been synthesized by two methods to select a method of higher yield. The newly synthesized compounds have been characterized by IR, CHNS analysis, LC-MS and 1H NMR and also screened for antibacterial activity. |
Page(s): | 1491-1495 |
URI: | http://hdl.handle.net/123456789/12852 |
ISSN: | 0975-0983(Online); 0376-4699(Print) |
Appears in Collections: | IJC-B Vol.50B(10) [October 2011] |
Files in This Item:
File | Description | Size | Format | |
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IJCB 50B(10) 1491-1495.pdf | 67.83 kB | Adobe PDF | View/Open |
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