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Indian Journal of Traditional Knowledge (IJTK) >
IJTK Vol.10 [2011] >
IJTK Vol.10(4) [October 2011] >
| Title: | A clinical study on the management of generalized anxiety disorder with Vaca (Acorus calamus) |
| Authors: | Bhattacharyya, D
Sur, TK
Lyle, N
Jana, U
Debnath, PK |
| Keywords: | Anxiety disorders
Psychological stress
Depression
Vac
Acorus calamus
Ayurvedic medicine |
| Issue Date: | Oct-2011 |
| Publisher: | NISCAIR-CSIR, India |
| IPC Code: | Int. Cl.8: A01D 8/00, A01D 22/23, A01D 10/09, A01D 12/24, A01D 13/25, A01D 22/22, A01D 22/00 |
| Abstract: | In Ayurveda, Vaca (Acorus calamus, Family: Araceae), is reputed
for its beneficial effects in various neurological disorders. The present
investigation was undertaken to evaluate the role of 70% hydro-ethanolic
extract of Vaca or Acorus calamus (ACE) on generalized
anxiety disorder (GAD) in human. Hamilton’s
Brief Psychiatric Rating Scale (BPRS) and thorough clinical investigations were
used to screen the subjects. Thirty-three participants (20 male
and 13 female; average age 36.2 yrs) were medicated with ACE in a fixed dose
regime (500 mg/capsule, twice daily, p.o. after meal). They were thoroughly
investigated clinically and using standard questionnaires based on different
psychological rating scale at baseline (day 0), mid-term (day 30) and final
(day 60). The scale
also includes a number of direct queries about current levels of experienced
stress. Moreover, the questions are of a general nature and hence are
relatively free of content specific to any subpopulation group. The observations exhibited that,
ACE not only significantly (p<0.001) attenuated anxiety related disorders
but it also significantly (p<0.001) reduced stress phenomenon and its
correlated depression. ACE further significantly (p<0.001) improved the
willingness to adjustment. Therefore, it may be concluded that Vaca may be useful in the treatment of GAD
in human and may be a promising anxiolytic agent in near future. |
| Page(s): | 668-671 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-1068 (Online); 0972-5938 (Print) |
| Source: | IJTK Vol.10(4) [October 2011]
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