NISCAIR Online Periodicals Repository

Research Journals >
Indian Journal of Traditional Knowledge (IJTK) >
IJTK Vol.10 [2011] >
IJTK Vol.10(4) [October 2011] >

Title: Evaluation of adaptogenic activity profile of a compound Ayurvedic formulation - Amalakayas Rasayana
Authors: Samarakoon, SMS
Chandola, HM
Ravishankar, B
Ashok, BK
Gupta, Varun B
Keywords: Amalakayas Rasayana
Adaptogenic activity
Ulcer index
Issue Date: Oct-2011
Publisher: NISCAIR-CSIR, India
IPC CodeInt. Cl.8: H01R 25/00, G0L 1/00, A01D 20/48, A01D 20/76, A01D 7/12, A01D 4/52
Abstract: The present study was undertaken to evaluate adaptogenic activity profile of a classical compound Ayurvedic formulation Amalakayas Rasayana in experimental animals. Amalakayas Rasayana (AR) was tested for its adaptogenic activity by determining anti-stress and anti-ulcer activity in forced swimming induced hypothermia and stress induced gastric ulcers. AR was administered in the dose of 270 mg/kg orally for 7 consecutive days prior to forced swimming induced hypothermia and stress ulcers. The adaptogenic and anti-ulcer activities were assessed by determining and comparing the changes in rectal temperature, ponderal changes, ulcer index, haematological parameters and anti-oxidant activity in the test drug group with that of stress control group as well as vehicle control group. In forced swimming hypothermia pre-treatment with AR caused significant attenuation of rectal temperature when compared with both stress control and vehicle control groups. It has shown a significant reduction in ulcer index and lipid peroxidation. Moreover, AR did show a significant increase in total glutathione content. The results suggest that AR possesses significant adaptogenic and anti-stress activity which could be either due to attenuation of stress induced stimulation of HPA axis and cytoprotective action of the test formulation.
Page(s): 661-667
CC License:  CC Attribution-Noncommercial-No Derivative Works 2.5 India
ISSN: 0975-1068 (Online); 0972-5938 (Print)
Source:IJTK Vol.10(4) [October 2011]

Files in This Item:

File Description SizeFormat
IJTK 10(4) 661-667.pdf172.11 kBAdobe PDFView/Open
 Current Page Visits: 490 
Recommend this item


Online Submission of Articles |  NISCAIR Website |  National Knowledge Resources Consortium |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2015 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 163035 since 01-Sep-2015  Last updated on 21-Jun-2016Webmaster: