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Title: Developmental toxicity of nonylphenol in zebrafish (<i>Danio rerio</i>) embryos
Authors: Ali, Tamer El-Sayed
Legler, Juliette
Keywords: Nonylphenol
Non-estrogenic action
Developmental abnormalities
Issue Date: Aug-2011
Publisher: NISCAIR-CSIR, India
Abstract: Present study reports the response of zebrafish embryos exposed <i>in vivo</i> to graded concentrations of Nonylphenol (NP), ranging from high lethal levels to lower, more environmentally relevant levels. Embryos treated with NP showing developmental abnormalities and morphological alterations in a dose-dependent pattern. Results suggest that early exposure to NP can cause direct and delayed mortalities or even non-lethal malformations at doses more than 0.3 μM, while EC<sub>50</sub> was shown to be 1 μM after 6 days of exposure.
Description: 509-515
ISSN: 0975-1033 (Online); 0379-5136 (Print)
Appears in Collections:IJMS Vol.40(4) [August 2011]

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