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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Biochemistry and Biophysics (IJBB) >
IJBB Vol.48 [2011] >
IJBB Vol.48(4) [August 2011] >
| Title: | Recent Advances in i-Gene Tools and Analysis: Microarrays, Next Generation Sequencing and Mass Spectrometry |
| Authors: | Moorhouse, Michael J
Sharma, Hari S |
| Keywords: | I-Gene analysis
Microarrays
Next Generation Sequencing
Mass spectrometry |
| Issue Date: | Aug-2011 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Recent advances in technology and associated methodology have made
the current period one of the most exciting in molecular biology and medicine.
Underlying these is an appreciation that modern research is driven by
increasing large amounts of data being interpreted by interdisciplinary
collaborative teams which are often geographically dispersed. The availability
of cheap computing power, high speed informatics networks and high quality
analysis software has been essential to this as has the application of modern
quality assurance methodologies. In this review, we discuss the application of
modern ‘High-Throughput’ molecular biological technologies such as
‘Microarrays’ and ‘Next Generation Sequencing’ to scientific and biomedical
research as we have observed. Furthermore in
this review, we also offer some guidance that enables the reader as to
understand certain features of these as well as new strategies and help them to
apply these i-Gene tools in their endeavours successfully. Collectively, we
term this ‘i-Gene Analysis’. We also offer predictions as to the developments
that are anticipated in the near and more distant future.
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| Page(s): | 215-225 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0959 (Online); 0301-1208 (Print) |
| Source: | IJBB Vol.48(4) [August 2011]
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