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Title: Synthesis and antimicrobial activity of linked heterocyclics containing pyrazole-pyrimidine rings
Authors: Reddy, Ch Sanjeeva
Devi, M Vani
Kumar, G Rajesh
Rao, L Sanjeeva
Nagaraj, A
Keywords: Pyrazole;Pyrimidine;Antibacterial activity;Antifungal activity
Issue Date: Sep-2011
Publisher: NISCAIR-CSIR, India
Abstract: New series of 4-(aryl/hetaryl)-6-(3,5-dimethyl-1-phenyl-1H-4-pyrazolyl)-2-pyrimidinamine 5a-j has been prepared and confirmed by IR, NMR, MS and elemental analyses. All the synthesized compounds have been tested for their antimicrobial activity against bacteria and fungi. Among the synthesized compounds, the compounds containing 4-nitrophenyl 5c, 2-furyl 5h and 2-thiazolyl 5j at 6-position of pyrimidine ring are highly active against all the organisms employed.
Page(s): 1181-1186
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.50B(09) [September 2011]

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