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Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.49 [2011] >
IJEB Vol.49(09) [September 2011] >
| Title: | Analgesic activity of the aqueous seed extract of Hunteria umbellata (K. Schum.) Hallier f. in rodents |
| Authors: | Adeyemi, Olufunmilayo Olaide
Adeneye, Adejuwon Adewale
Alabi, Tope Elizabeth |
| Keywords: | Analgesic activity
Aqueous seed extract
Hunteria umbellata
Rodents |
| Issue Date: | Sep-2011 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | The analgesic effect and possible
mechanism(s) of action of 50-200 mg/kg of the aqueous seed extract of H. umbellata
(HU) were investigated in different experimental models of analgesia using the
tail flick, tail immersion, acetic acid-induced writhing tests and
formalin-induced algesia. Oral pre-treatment with 50-200 mg/kg of HU caused
significant and dose related analgesic effect in the treated rats in all the
experimental models used. This analgesia was mediated via central and
peripheral mechanisms. Overall, the results showed that HU possesses analgesic
effect which lends support to its folkloric use in the local management of
pain. |
| Page(s): | 698-703 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Source: | IJEB Vol.49(09) [September 2011]
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