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Indian Journal of Biochemistry and Biophysics (IJBB) >
IJBB Vol.44 [2007] >
IJBB Vol.44(5) [October 2007] >
| Title: | Cellular AATF Gene: Armour against HIV-1 |
| Authors: | Kaul, Deepak |
| Keywords: | HIV-1 RNomics
Cellular AATF gene
CD4 Lymphopenia |
| Issue Date: | Oct-2007 |
| Publisher: | CSIR |
| Abstract: | Outcome of HIV-1 infection at the cellular level is decided by the orchestrated balance that exists between cellular nucleic acid-based adaptive immune mechanism involving non-coding micro RNAs (miRNAs) and offensive tactics of
HIV-1 to suppress this host cellular immunity. In this context, the review explains the importance of a novel miRNA encoded exclusively and conspicuously by HIV-1 genome that has the ability to specifically target cellular AATF gene recognized to play a crucial role in the maintenance of adaptive immunity at nucleic acid level against HIV-1 invasion. |
| Page(s): | 276-278 |
| ISSN: | 0301-1208 |
| Source: | IJBB Vol.44(5) [October 2007]
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