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|Title:||Cellular AATF Gene: Armour against HIV-1|
|Keywords:||HIV-1 RNomics;Cellular AATF gene;CD4 Lymphopenia|
|Abstract:||Outcome of HIV-1 infection at the cellular level is decided by the orchestrated balance that exists between cellular nucleic acid-based adaptive immune mechanism involving non-coding micro RNAs (miRNAs) and offensive tactics of HIV-1 to suppress this host cellular immunity. In this context, the review explains the importance of a novel miRNA encoded exclusively and conspicuously by HIV-1 genome that has the ability to specifically target cellular AATF gene recognized to play a crucial role in the maintenance of adaptive immunity at nucleic acid level against HIV-1 invasion.|
|Appears in Collections:||IJBB Vol.44(5) [October 2007]|
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|IJBB 44(5) (2007) 276-278.pdf||162.01 kB||Adobe PDF||View/Open|
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