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IJBB Vol.44(5) [October 2007] >


Title: Cellular AATF Gene: Armour against HIV-1
Authors: Kaul, Deepak
Keywords: HIV-1 RNomics
Cellular AATF gene
CD4 Lymphopenia
Issue Date: Oct-2007
Publisher: CSIR
Abstract: Outcome of HIV-1 infection at the cellular level is decided by the orchestrated balance that exists between cellular nucleic acid-based adaptive immune mechanism involving non-coding micro RNAs (miRNAs) and offensive tactics of HIV-1 to suppress this host cellular immunity. In this context, the review explains the importance of a novel miRNA encoded exclusively and conspicuously by HIV-1 genome that has the ability to specifically target cellular AATF gene recognized to play a crucial role in the maintenance of adaptive immunity at nucleic acid level against HIV-1 invasion.
Page(s): 276-278
ISSN: 0301-1208
Source:IJBB Vol.44(5) [October 2007]

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