NISCAIR Online Periodicals Repository

Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.50B [2011] >
IJC-B Vol.50B(08) [August 2011] >

Title: Sodium borohydride / methoxydiethylborane mediated syn-1,3-stereoselective total synthesis of Herbarumin-III
Authors: Yadav, J S
Narasimhulu, G
Reddy, Y Vikram
Reddy, B V Subba
Ghamdi, Ahmad Al Khazim Al
Keywords: Macrolactone
Sharpless epoxidation
Stereoselective syn-1,3-reduction
Ring-closing metathesis (RCM)
Issue Date: Aug-2011
Publisher: NISCAIR-CSIR, India
Abstract: A simple and efficient stereoselective total synthesis of 10-membered macrolide, herbarumin-III is described. The key steps involved in this synthesis are the selective terminal alkylation of ethyl acetoacetate with ethyl bromide, Sharpless epoxidation, NaBH4/Et2BOMe mediated stereoselective syn-1,3-asymmetric reduction, esterification and olefin metathesis.
Page(s): 1075-1082
CC License:  CC Attribution-Noncommercial-No Derivative Works 2.5 India
ISSN: 0975-0983(Online); 0376-4699(Print)
Source:IJC-B Vol.50B(08) [August 2011]

Files in This Item:

File Description SizeFormat
IJCB 50B(8) 1075-1082.pdf108.46 kBAdobe PDFView/Open
 Current Page Visits: 138 
Recommend this item


Online Submission of Articles |  NISCAIR Website |  National Knowledge Resources Consortium |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2015 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 164389 since 01-Sep-2015  Last updated on 21-Jun-2016Webmaster: