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Title: Comparative study on antibacterial activity of ascidians, <i style="">Polyandrocarpa indica </i>Michaelsen and <i style="">Phallusia arabica </i>Savigny from Tuticorin coast of India
Authors: Ganesan, K.
Bragadeeswaran, S.
Balasubramanian, T.
Keywords: Polyandrocarpa indica
Phallusia arabica
Antibacterial activity
Issue Date: Jun-2011
Publisher: NISCAIR-CSIR, India
Abstract: Marine ascidians contain antibacterial agents of relevance to either antifouling technology or clinical pharmacology. In the present study two ascidians <i style="">Polyandrocarpa indica<b style=""> </b></i>and <i style="">Phallusia arabica<b style=""> </b></i>were examined for their antibacterial activity against ten bacterial pathogens. Antimicrobial<b style=""> </b>activity of the crude extract of ascidians shows inhibitory activity against almost all the strains. However, methnolic extract of <i style="">P. arabica </i>shows prominent antibacterial activity against than that of <i>P. indica</i>. Maximum inhibition zone (17 mm) was observed against <i>Salmonella typhi </i>in the crude methanol extract of <i>P. arabica </i>and the minimum inhibition zone (1 mm) was noticed against <i style="">P. mirabilis </i>and <i style="">P. aeruginosa </i>in the<i style=""> </i>ethyl acetate and diethyl ether extract of <i style="">P. indica.</i> In <i style="">P. indica</i> the crude extract range of inhibition of bacteria varied from 1-12 mm. Based on observed zone of inhibition, present study revealed that <i style="">P. arabica </i>extract are more effective than <i style="">P. indica.</i>
Description: 438-442
ISSN: 0975-1033 (Online); 0379-5136 (Print)
Appears in Collections:IJMS Vol.40(3) [June 2011]

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