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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
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Research Journals >
Journal of Scientific and Industrial Research (JSIR) >
JSIR Vol.66 [2007] >
JSIR Vol.66(03) [March 2007] >
| Title: | Emerging trends in tuberculosis therapy—A review |
| Authors: | Agrawal, Yadvendra K
Bhatt, Hardik G
Raval, Hitesh G
Oza, Pratik M
Vaidya, Hitesh B |
| Keywords: | Antimycobacterial agents
Cell envelope
Drugs, MIC
Mycobacterium tuberculosis
Therapeutic agents
Targets |
| Issue Date: | Mar-2007 |
| Publisher: | CSIR |
| Abstract: | Tuberculosis is one of the most devastating bacterial disease having high rates of morbidity and mortality.
Mycobacterium tuberculosis invades the host immune system and persists in pulmonary granulomas. Review presents
bacterial cell wall or envelope structure, drug targets against M. tuberculosis and novel therapeutics agents like quinolone,
pyrimidine, nitroimidazopyran and oxazolidinone derivatives. This review also focuses on the newer untouched targets like
immunomodulators and isocitrate lyase inhibitors, which can be further exploited. |
| Page(s): | 191-208 |
| ISSN: | 0022-4456 |
| Source: | JSIR Vol.66(03) [March 2007]
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