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Indian Journal of Natural Products and Resources (IJNPR)
[Formerly Natural Product Radiance (NPR)] >
IJNPR Vol.2 [2011] >
IJNPR Vol.2(2) [June 2011] >
| Title: | Antibacterial and cytotoxic activities of Spondias pinnata (Linn. f.) Kurz fruit extract |
| Authors: | Muhammad, Ashif
Rahman, Md. Shafiur
Kabir, ANM Hamidul
Kabir, Shaila
Hossain, Md. Khalid |
| Keywords: | Spondias pinnata
Anacardiaceae
Antibacterial
Cytotoxic
Fruit |
| Issue Date: | Jun-2011 |
| Publisher: | NISCAIR-CSIR, India |
| IPC Code: | A61K 36/00, A61P 31/04 |
| Abstract: | The
plant Spondias pinnata (Linn. f.) Kurz belonging to Anacardiaceae
family, is used as a medicinal agent in Bangladesh. In the present
investigation, attempt was undertaken to study the antibacterial potency and
cytotoxic activity of 80% ethanol extract of its fruit. The antibacterial
activity was performed by the disc diffusion method and cytotoxicity was
observed by brine shrimp lethality bioassay. The fruit extract exhibited mild
to potent antibacterial activity against some Gram-positive and Gram-negative
bacteria at a concentration of 500 µg/disc. Among
them Pseudomonas aeruginosa and Staphylococcus epidermidis shows promising result. The ethanolic extract revealed strong cytotoxicity having
LC50 of 2.12±0.09 µg/ml. |
| Page(s): | 265-267 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-1033 (Online); 0379-5136 (Print) |
| Source: | IJNPR Vol.2(2) [June 2011]
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