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Title: Immunostimulatory effects of curcumin in fish, Labeo rohita (H.)
Authors: Behera, T
Swain, P
Sahoo, S K
Mohapatra, D
Das, B K
Keywords: Curcumin;Curcuma longa;Fish;Immune response;Immuomodulatory;Indian major carp;Labeo rohita;Turmeric
Issue Date: Jun-2011
Publisher: NISCAIR-CSIR, India
IPC Code: A61K 36/9066, A61P 31/04, A61P 37/00
Abstract: Curcumin, an orange-yellow phytochemical, hydrophobic and polyphenolic compound of turmeric (Curcuma longa Linn.), has been known to be a potent immunomodulatory agent in mice, horse, human and other higher vertebrates. In the present study, we have found its immunostimulatory properties in fish Labeo rohita (H.). Curcumin at low doses (15 and 1.5 μg) significantly (P<0.05) increased some non-specific immune parameters such as respiratory burst, myeloperoxidase, haemagglutination, haemolytic and bacterial agglutination activities up to 21 days post administration without any side effects. It has also further increased bacterial agglutination activities in Aeromonas hydrophila injected fishes primed with low dose (15 μg) curcumin.
Page(s): 184-188
ISSN: 0975-1033 (Online); 0379-5136 (Print)
Appears in Collections:IJNPR Vol.2(2) [June 2011]

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