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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
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Research Journals >
Indian Journal of Natural Products and Resources (IJNPR)
[Formerly Natural Product Radiance (NPR)] >
IJNPR Vol.2 [2011] >
IJNPR Vol.2(2) [June 2011] >
| Title: | Evaluation of anti-inflammatory activity of Ficus carica Linn. leaves |
| Authors: | Patil, Vikas V
Patil, Vijay R |
| Keywords: | Leaves
Ficus carica
Moraceae
Anti-inflammatory
Indomethacin |
| Issue Date: | Jun-2011 |
| Publisher: | NISCAIR-CSIR, India |
| IPC Code: | A61K 36/00, A61P 29/00 |
| Abstract: | The aim of the present study was to explore the probable
anti-inflammatory effect of petroleum ether (PEE), chloroform (CE) and ethanol
(EE) extracts obtained from the leaves of Ficus
carica Linn. Anti-inflammatory activity was studied by carrageenan-induced
rat paw edema and cotton pellet granuloma methods. The extracts were
administered orally in doses of 300 and 600 mg/kg/day of body weight to healthy
animals. The ethanolic extract (EEFC-II) 600 mg/kg exhibited maximum
anti-inflammatory effect, which is 75.90%
in acute inflammation and in chronic study showed 71.66% reduction in granuloma
weight. The petroleum ether (PEE), chloroform (CE) and ethanol (EE) extracts
significantly reduced carrageenan-induced paw edema and cotton pellet granuloma
method in rats. These extracts showed a greater anti-inflammatory effect
comparative to standard drug Indomethacin. |
| Page(s): | 151-155 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-1033 (Online); 0379-5136 (Print) |
| Source: | IJNPR Vol.2(2) [June 2011]
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