|
NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Chemistry -Section A (IJC-A) >
IJC-A Vol.46A [2007] >
IJC-A Vol.46A(06) [June 2007] >
| Title: | Simultaneous determination of ascorbic acid, dopamine and uric acid using PEDOT polymer modified electrodes |
| Authors: | Jeyalakshmi, S Radha
Kumar, S Senthil
Mathiyarasu, J
Phani, K L N
Yegnaraman, V |
| Issue Date: | Jun-2007 |
| Publisher: | CSIR |
| IPC Code: | Int. Cl. ⁸ G01N27/30; G01N33/50 |
| Abstract: | Dopamine, uric acid and ascorbic acid have been determined simultaneously on a poly(3,4-ethylenedioxythiophene) modified electrode using electrochemical techniques. On a bare glassy car-bon electrode, all three undergo oxidation and appear as a single peak at around 200 mV, whereas on the modified electrode, dis-tinct peaks with clear potential separation are observed, paving way for their simultaneous determination. Detection limits of 7.4 μM, 1.2 M and 1.4 μM for ascorbic acid, dopamine and uric acid, respectively are observed by pulse voltammetry. The possible interference from creatinine, norepinephrine, epinephrine, glu-cose, ascorbic acid, urea, oxalate and acetylsalicylic acid (aspirin) has been tested. The protocol developed using this modified glassy carbon electrode has been evaluated using the human blood serum samples for the simultaneous determination of dopamine and uric acid. |
| Page(s): | 957-961 |
| ISSN: | 0376-4710 |
| Source: | IJC-A Vol.46A(06) [June 2007]
|
|
