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Title: Simultaneous determination of ascorbic acid, dopamine and uric acid using PEDOT polymer modified electrodes
Authors: Jeyalakshmi, S Radha
Kumar, S Senthil
Mathiyarasu, J
Phani, K L N
Yegnaraman, V
Issue Date: Jun-2007
Publisher: CSIR
IPC Code: Int. Cl. ⁸ G01N27/30; G01N33/50
Abstract: Dopamine, uric acid and ascorbic acid have been determined simultaneously on a poly(3,4-ethylenedioxythiophene) modified electrode using electrochemical techniques. On a bare glassy car-bon electrode, all three undergo oxidation and appear as a single peak at around 200 mV, whereas on the modified electrode, dis-tinct peaks with clear potential separation are observed, paving way for their simultaneous determination. Detection limits of 7.4 μM, 1.2 M and 1.4 μM for ascorbic acid, dopamine and uric acid, respectively are observed by pulse voltammetry. The possible interference from creatinine, norepinephrine, epinephrine, glu-cose, ascorbic acid, urea, oxalate and acetylsalicylic acid (aspirin) has been tested. The protocol developed using this modified glassy carbon electrode has been evaluated using the human blood serum samples for the simultaneous determination of dopamine and uric acid.
Page(s): 957-961
ISSN: 0376-4710
Appears in Collections:IJC-A Vol.46A(06) [June 2007]

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