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Title: Synthesis, characterization and antimicrobial activity of some 3-(2-(1H-benzo[d]imidazol-2-yl)phenyl)-2-arylthiazolidin-4-ones
Authors: Desai, N C
Bhatt, Nayan
Kumar, Mukesh
Makwana, Atul
Keywords: 2-Aminobenzoic acid;Benzene-1,2-diamine;Benzimidazole;Thiazolidinone;Antibacterial activity;Antifungal activity
Issue Date: Jul-2011
Publisher: NISCAIR-CSIR, India
Abstract: As a part of systematic investigation of synthesis, characteriza­tion and biological activities, several new 3-(2-(1H-benzo­[d]imidazol-2-yl)phenyl)-2-arylthiazolidin-4-ones 3a-l, have been synthesized from Schiff bases of benzimidazoles 2a-l, which have been prepared by condensation of different aldehydes with 2-(1H-benzo[d]imidazol-2-yl)benzenamine 1. Compound 1 was obtained by the reaction of 2-aminobenzoic acid and benzene-1,2-diamine. All the synthesized compounds have been evaluated for their antibacterial and antifungal activities against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pyogenes, Candida albicans, Asperigillus niger and Asperigillus clavatus.
Page(s): 941-945
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.50B(07) [July 2011]

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