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|Title:||Stereoselective preparation of a key intermediate toward the synthesis of nelfinavir|
Kumar, Ch Naveen
|Abstract:||A stereoselective synthesis of an intermediate that can be elaborated into the potent HIV-protease inhibitor, nelfinavir, is described. The key step of the reaction sequence is the stereoselective preparation of a bromosulfonamide from an olefin using the sulfilimine moiety as an intramolecular nucleophile.|
|Appears in Collections:||IJC-B Vol.50B(06) [June 2011]|
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