Please use this identifier to cite or link to this item:
Title: Stereoselective preparation of a key intermediate toward the synthesis of nelfinavir
Authors: Raghavan, Sadagopan
Kumar, Ch Naveen
Keywords: Nelfinavir;Sulfilimine;Bromosulfonamidation;Pummerer reaction
Issue Date: Jun-2011
Publisher: NISCAIR-CSIR, India
Abstract: A stereoselective synthesis of an intermediate that can be elaborated into the potent HIV-protease inhibitor, nelfinavir, is described. The key step of the reaction sequence is the stereoselective preparation of a bromosulfonamide from an olefin using the sulfilimine moiety as an intramolecular nucleophile.
Page(s): 821-828
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.50B(06) [June 2011]

Files in This Item:
File Description SizeFormat 
IJCB 50B(6) 821-828.pdf154.87 kBAdobe PDFView/Open

Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.