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IJEB Vol.49(06) [June 2011] >


Title: Cellular reprogramming of somatic cells
Authors: Sumer, Huseyin
Liu, Jun
Verma, Paul J
Keywords: Epigenetic reprogramming
Lineage-specific reprogramming
Nuclear reprogramming
Pluripotency
Somatic cell
Stem cell
Issue Date: Jun-2011
Publisher: NISCAIR-CSIR, India
Abstract: The process of ‘cell reprogramming’ can be achieved by somatic cell nuclear transfer, cell fusion with embryonic stem cells, exposure to stem cell extracts, or by inducing pluripotentcy mediated by defined factors giving rise to what are termed induced pluripotent stem cells. More recently, the fate of a somatic cell can be directly induced to uptake other cell fates, termed lineage-specific reprogramming, without the need to de-differentiate the cells to a pluripotent state. In this review we will describe the different methods of reprogramming somatic cells
Page(s): 409-415
CC License:  CC Attribution-Noncommercial-No Derivative Works 2.5 India
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Source:IJEB Vol.49(06) [June 2011]

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