|
NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.49 [2011] >
IJEB Vol.49(06) [June 2011] >
| Title: | Cellular reprogramming of somatic cells |
| Authors: | Sumer, Huseyin
Liu, Jun
Verma, Paul J |
| Keywords: | Epigenetic reprogramming
Lineage-specific reprogramming
Nuclear reprogramming
Pluripotency
Somatic cell
Stem cell |
| Issue Date: | Jun-2011 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | The process of ‘cell
reprogramming’ can be achieved by somatic cell nuclear transfer, cell fusion
with embryonic stem cells, exposure to stem cell extracts, or by inducing
pluripotentcy mediated by defined factors giving rise to what are termed
induced pluripotent stem cells. More recently, the fate of a somatic cell can
be directly induced to uptake other cell fates, termed lineage-specific
reprogramming, without the need to de-differentiate the cells to a pluripotent
state. In this review we will describe the different methods of reprogramming
somatic cells |
| Page(s): | 409-415 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Source: | IJEB Vol.49(06) [June 2011]
|
|
