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NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.49 [2011] >
IJEB Vol.49(06) [June 2011] >
| Title: | Stem cell therapies for type 1 diabetes mellitus |
| Authors: | Voltarelli, Júlio C
Couri, Carlos E B
Rodrigues, Maria C
Moraes, Daniela A
Stracieri, Ana-Beatriz P L
Pieroni, Fabiano
Navarro, George
Leal, Angela M O
Simões, Belinda P |
| Keywords: | Diabetes mellitus
HSCT
Immunosupression
Stem cell |
| Issue Date: | Jun-2011 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | The present review discusses the use of autologous hematopoietic stem
cell transplantation (HSCT) for the treatment of diabetes mellitus type 1 (DM
1). It has been observed that high dose immunosuppression followed by HSCT
shows better results among other immunotherapeutic treatments for the disease
as the patients with adequate beta cell reserve achieve insulin independence.
However, this response is not maintained and reoccurrence of the disease is
major a major challenge to use HSCT in future to prevent or control relapse of
DM 1. |
| Page(s): | 395-400 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Source: | IJEB Vol.49(06) [June 2011]
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