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Title: Alpha-adrenergic receptor blocking effect of <i style="">Cleistanthus collinus </i>(Roxb.) Benth. and Hook f. leaf extract on guinea pig isolated smooth muscle preparations
Authors: Kumar, M Ravindra
Ramaswamy, S
Jayanthi, M
Raveendran, R
Keywords: α-adrenergic
<i style="">Cleistanthus collinus</i>
Issue Date: May-2011
Publisher: NISCAIR-CSIR, India
Abstract: Aqueous extract of <i style="">C. collinus</i> leaves inhibited norepinephrine induced contraction in guinea pig vas deferens and aortic strip in a dose-dependent manner. Inhibition of acetylcholine induced contraction in ileum was dose independent. <i style="">C. collinus</i> extract <i style="">per se</i> had no effect on isolated guinea pig vas deferens and aortic strip, but inhibited norepinephrine induced contraction in a dose-dependent manner probably by its antagonist action on α-adrenergic receptor. It had inconsistent effect on guinea pig ileum <i style="">in vitro</i> preparation.
Description: 339-342
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.49(05) [May 2011]

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