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IJBB Vol.48(2) [April 2011] >


Title: MAPS: An interactive web server for membrane annotation of transmembrane protein structures
Authors: Cheema, Jitender
Basu, Gautam
Keywords: Web server MAPS
Transmembrane proteins
Membrane flexibility
Issue Date: Apr-2011
Publisher: NISCAIR-CSIR, India
Abstract: The exact positioning of the membrane in transmembrane (TM) proteins plays important functional roles. Yet, the structures of TM proteins in protein data bank (pdb) have no information about the explicit position of the membrane. Using a simple hydrophobic lipid-protein mismatch energy function and a flexible lipid/water boundary, the position of lipid bilayer for representative TM proteins in pdb have been annotated. A web server called MAPS (Membrane Annotation of Protein Structures; available at: http://www.boseinst.ernet.in/gautam/maps) has been set up that allows the user to interactively analyze membrane-protein orientations of any uploaded pdb structure with user-defined membrane flexibility parameters.
Page(s): 106-110
CC License:  CC Attribution-Noncommercial-No Derivative Works 2.5 India
ISSN: 0975-0959 (Online); 0301-1208 (Print)
Source:IJBB Vol.48(2) [April 2011]

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