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Indian Journal of Biochemistry and Biophysics (IJBB) >
IJBB Vol.48 [2011] >
IJBB Vol.48(2) [April 2011] >
| Title: | MAPS: An interactive web server for membrane annotation of transmembrane protein structures |
| Authors: | Cheema, Jitender
Basu, Gautam |
| Keywords: | Web server MAPS
Transmembrane proteins
Membrane flexibility |
| Issue Date: | Apr-2011 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | The exact positioning of the membrane in
transmembrane (TM) proteins plays important functional roles. Yet, the
structures of TM proteins in protein data bank (pdb) have no information about
the explicit position of the membrane. Using a simple hydrophobic lipid-protein
mismatch energy function and a flexible lipid/water boundary, the position of
lipid bilayer for representative TM proteins in pdb have been annotated. A web
server called MAPS (Membrane Annotation of Protein Structures; available at:
http://www.boseinst.ernet.in/gautam/maps) has been set up that allows the user
to interactively analyze membrane-protein orientations of any uploaded pdb
structure with user-defined membrane flexibility parameters. |
| Page(s): | 106-110 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0959 (Online); 0301-1208 (Print) |
| Source: | IJBB Vol.48(2) [April 2011]
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