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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
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Research Journals >
Indian Journal of Natural Products and Resources (IJNPR)
[Formerly Natural Product Radiance (NPR)] >
IJNPR Vol.2 [2011] >
IJNPR Vol.2(1) [March 2011] >
| Title: | Isolation and characterization of bioactive compounds from marine bacteria |
| Authors: | Devi, N K Asha
Rajendran, R
Sundaram, S Karthik |
| Keywords: | Anti-bacterial
Antagonistic
Bioactive compounds
Drechslerine
Marine bacteria
Sativenediol |
| Issue Date: | Mar-2011 |
| Publisher: | NISCAIR-CSIR, India |
| IPC Code: | Int. cl. (2011.01) -- A61K 35/74, A61P 31/04 |
| Abstract: | With a huge volume of unexplored wealth, marine environment dazzles
out to be a very good source, capable of answering many unsolved questions and
a treasure of unresolved mysteries. In this work coastal water samples were
collected from Thiruchendur, Thoothukudi and Kanyakumari, Tamil Nadu. From
these samples, organisms were isolated by spread plate technique using marine
agar. About 21 bacterial isolates were isolated and were screened primarily
through agar diffusion method, of which only 6 isolates exerted an inhibitory
effect against the target organisms were selected for antimicrobial analysis. Their
supernatants were used to study the antagonistic activity against target
organisms (Salmonella typhi, Enterobacter sp., Pseudomonas sp., Streptococcus mutans, Staphylococcus epidermidis and S. aureus). Cell free extracts of two
organisms Alteromonas sp. and Rhodopseudomonas sp. identified
in the isolates were found antagonistic against all the test organisms. Both
the supernatants were checked with Nuclear Magnetic Spectroscopy for
characterizing the active factor. The cell free supernatant from the first one
was suspected to contain the compound similar to Drechslerine A and the other
supernatant was found suspected to contain the compound similar to that of
cis-Sativenediol. |
| Page(s): | 59-64 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-1033 (Online); 0379-5136 (Print) |
| Source: | IJNPR Vol.2(1) [March 2011]
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