Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/11541
Title: Isolation and characterization of bioactive compounds from marine bacteria
Authors: Devi, N K Asha
Rajendran, R
Sundaram, S Karthik
Keywords: Anti-bacterial
Antagonistic
Bioactive compounds
Drechslerine
Marine bacteria
Sativenediol
Issue Date: Mar-2011
Publisher: NISCAIR-CSIR, India
Series/Report no.: <b style="">Int. cl.<sup> </sup>(2011.01) </b><b style="">--</b> A61K 35/74, A61P 31/04
Abstract: With a huge volume of unexplored wealth, marine environment dazzles out to be a very good source, capable of answering many unsolved questions and a treasure of unresolved mysteries. In this work coastal water samples were collected from Thiruchendur, Thoothukudi and Kanyakumari, Tamil Nadu. From these samples, organisms were isolated by spread plate technique using marine agar. About 21 bacterial isolates were isolated and were screened primarily through agar diffusion method, of which only 6 isolates exerted an inhibitory effect against the target organisms were selected for antimicrobial analysis. Their supernatants were used to study the antagonistic activity against target organisms (<i>Salmonella typhi, Enterobacter </i>sp.<i>, Pseudomonas </i>sp.,<i style=""> Streptococcus mutans</i>,<i style=""> Staphylococcus epidermidis </i>and<i style=""> S. aureus</i>). Cell free extracts of two organisms <i>Alteromonas</i> sp. and <i style="">Rhodopseudomonas </i>sp.<i> </i>identified in the isolates were found antagonistic against all the test organisms. Both the supernatants were checked with Nuclear Magnetic Spectroscopy for characterizing the active factor. The cell free supernatant from the first one was suspected to contain the compound similar to Drechslerine A and the other supernatant was found suspected to contain the compound similar to that of cis-Sativenediol.
Description: 59-64
URI: http://hdl.handle.net/123456789/11541
ISSN: 0975-1033 (Online); 0379-5136 (Print)
Appears in Collections:IJNPR Vol.2(1) [March 2011]

Files in This Item:
File Description SizeFormat 
IJNPR 2(1) 59-64.pdf169.74 kBAdobe PDFView/Open


Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.