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Indian Journal of Biotechnology (IJBT) >
IJBT Vol.10 [2011] >
IJBT Vol.10(2) [April 2011] >
| Title: | Exploration of Y-chromosome specific markers to discover SNP associated with sub fertility traits in dairy bulls |
| Authors: | Mukhopadhyay, C S
Gupta, A K
Yadav, B R
Mohanty, T K |
| Keywords: | Buffalo
Bulls Y-chromosome
SNP
Sub fertility |
| Issue Date: | Apr-2011 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | The present study was designed to identify
single nucleotide polymorphism (SNP) in Y-chromosome specific genes, namely,
sex determining region, Y-encoded (SRY) and testis specific protein, Y-encoded
(TSPY) vis-à-vis, detection of association between the SNP and andrological
parameters (like, conception rate and per cent individual motility of semen). A
total of 106 bulls, belonging to Karan Fries (Holstein Friesian crossbreds
cattle), Sahiwal cattle and Murrah buffalo, were selected based on poor
reproductive performance (viz., libido, semen quality & freezability),
along with some control bulls with normal andrological parameters. Single
strand conformation polymorphism followed by sequencing of the different band
patterns revealed only a single novel SNP (Guanine to Adenine transition) in
the 4th intron of TSPY gene in Murrah buffalo. There was no
significant association between the genotypes and the andrological parameters
under study. Further study, encompassing larger number of animals distributed
over many farms, could reveal sizeable number of SNP and association with
spermatological parameters. |
| Page(s): | 178-182 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0967 (Online); 0972-5849 (Print) |
| Source: | IJBT Vol.10(2) [April 2011]
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