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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
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Research Journals >
Indian Journal of Biotechnology (IJBT) >
IJBT Vol.10 [2011] >
IJBT Vol.10(2) [April 2011] >
| Title: | Codon usage pattern of differentially expressed genes in Leishmania species |
| Authors: | Singh, Abhimanyu Kumar
Vidyarthi, Ambarish Sharan
Shankaracharya |
| Keywords: | Effective number of codons
Leishmania infantum
L. major
Mutational pressure
Relative synonymous codon usage
Translational selection |
| Issue Date: | Apr-2011 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Out of numerous genes, differentially
expressed genes of Leishmania major (299)
and L. infantum (241), essential for
their survival, have been studied for the analysis of synonymous codon usage
patterns. The role of translational selection and mutational biases were
analyzed through ENc plot and correspondence analysis. Present analysis
indicates that mutational pressure has a profound effect on codon usage pattern
in both the species of Leishmania
(with a minor variation). Beside this, natural and translational selections
also operate with a proper balance that makes the organism translationally more
efficient. |
| Page(s): | 188-195 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0967 (Online); 0972-5849 (Print) |
| Source: | IJBT Vol.10(2) [April 2011]
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