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Title: Saussurea heteromalla (D. Don) Hand.-Mazz.: A new source of arctiin, arctigenin and chlorojanerin
Authors: Saklani, Arvind
Sahoo, Manas Ranjan
Mishra, Prabhu Dutt
Vishwakarma, Ram
Keywords: Saussurea heteromalla;Arctiin;Arctigenin;Chloro-janerin;Anti-inflammatory;Anti-ulcer;Anti-viral
Issue Date: Apr-2011
Publisher: NISCAIR-CSIR, India
Abstract: Saussurea heteromalla (D. Don) Hand.-Mazz. (Asteraceae), a Himalayan herb, has been investigated phytochemically for the first time in detail and the plant is being reported here as a new source of two lignans, i.e. arctigenin and its glycoside arctiin, and one sequiterpene lactone, the chlorojanerin. The structures of these compounds, determined by UV spectra, LC-MS, 1H NMR and 13C NMR spectroscopy are discussed. These compounds have been found pharmacologically important; arctigenin and arctiin are known to have anti-inflammatory activity and chlorjanerin has been investigated for the anti-ulcer and anti-viral properties.
Page(s): 624-626
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.50B(04) [April 2011]

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