Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/11404
Title: Facile one-pot synthesis of novel 3-substituted-1, 6-dihydro-1,2,4-triazin-5-(2<i style="">H</i>)-ones from fatty acid hydrazides and their <i style="">in-vitro</i> antimicrobial activity
Authors: Farshori, Nida Nayyar
Banday, Mudasir Rashid
Ahmad, Anis
Khan, Asad Ullah
Rauf, Abdul
Keywords: Fatty acid hydrazides
1,2,4-triazin-5-ones
IR
<sup>1</sup>H NMR
MS
Antimicrobial activity
Issue Date: Apr-2011
Publisher: NISCAIR-CSIR, India
Abstract: A series of 3-substituted-1,6-dihydro-1,2,4-triazin-5(2<i style="">H</i>)-ones, have been synthesized using the cyclocondensation reaction of fatty acid hydrazides with 2-chloroacetamide in N,N-dimethylformamide medium. The structural elucidation of the synthesized compounds is based on IR, <sup>1</sup>H NMR, mass spectral data and elemental analysis. These compounds have been tested for their <i style="">in-vitro</i> antibacterial and antifungal activities. The MIC, MBC and MFC have also been determined.
Description: 605-610
URI: http://hdl.handle.net/123456789/11404
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.50B(04) [April 2011]

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