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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.50B [2011] >
IJC-B Vol.50B(04) [April 2011] >
| Title: | Facile one-pot synthesis of novel 3-substituted-1, 6-dihydro-1,2,4-triazin-5-(2H)-ones from fatty acid hydrazides and their in-vitro antimicrobial activity |
| Authors: | Farshori, Nida Nayyar
Banday, Mudasir Rashid
Ahmad, Anis
Khan, Asad Ullah
Rauf, Abdul |
| Keywords: | Fatty acid hydrazides
1,2,4-triazin-5-ones
IR
1H NMR
MS
Antimicrobial activity |
| Issue Date: | Apr-2011 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | A series of
3-substituted-1,6-dihydro-1,2,4-triazin-5(2H)-ones,
have been synthesized using the cyclocondensation reaction of fatty acid
hydrazides with 2-chloroacetamide in N,N-dimethylformamide medium. The
structural elucidation of the synthesized compounds is based on IR, 1H
NMR, mass spectral data and elemental analysis. These compounds have been
tested for their in-vitro
antibacterial and antifungal activities. The MIC, MBC and MFC have also been
determined. |
| Page(s): | 605-610 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.50B(04) [April 2011]
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