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IJEB Vol.49(04) [April 2011] >


Title: Anti-hyperlipidemic and antioxidant potential of different fractions of Terminalia arjuna Roxb. bark against PX- 407 induced hyperlipidemia
Authors: Subramaniam, Saravanan
Ramachandran, Subramaniam
Uthrapathi, Subasini
Gnamanickam, Victor Rajamanickam
Dubey, Govinda Prasad
Keywords: Antioxidant
Coronary heart disease
Hyperlipidemia
Poloxamer 407
Terminalia arjuna
Issue Date: Apr-2011
Publisher: NISCAIR-CSIR, India
Abstract: The three fractions diethyl ether, ethyl acetate and ethanol. of T. arjuna exerted hypolipidemic and antioxidative effects at two different doses levels of 175 and 350 mg/kg body weight in Poloxamer (PX)-407 induced hyperlipidemic albino Wistar rats. The hypolipidemic and antioxidant effects of T. arjuna fractions were noticed as EtOH>diethyl ether>ethyl acetate. The results suggest that ethanolic fraction of T. arjuna possesses the potent properties of being antioxidant and hypolipidemic than other fractions. In turn, it has therapeutic potential for the prevention of coronary arterial disease.
Page(s): 282-288
CC License:  CC Attribution-Noncommercial-No Derivative Works 2.5 India
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Source:IJEB Vol.49(04) [April 2011]

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