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Title: Induced Immunity against Haemolymph Proteins of Anopheles stephensi: Effects on Fecundity and Transmission Blocking of Malaria Parasite
Authors: Gulia, Monika
Gakhar, S K
Keywords: Anopheles
Issue Date: Oct-2003
Publisher: NISCAIR-CSIR, India
Abstract: Rabbit antibodies to nine antigens (100, 88, 80, 64, 55, 43, 29, 23 and 15 kDa),' derived from haemolymph of Anopheles stephensi mosquitoes after first gonotrophic cycle, tended to reduce the number of eggs produced by the mosquitoes and block the transmission of malaria parasite, Plasmodium vivax. Cross-reactivity of these antibodies was checked both by Western blotting and in vivo ELISA. In addition, effect of these antibodies on mortality, engorgement and hatchability in mosquitoes was also determined. The results indicated that haemolymph antibodies have the potential to disrupt the reproductive physiology of mosquitoes and further studies are needed with the target antigens.
Page(s): 543-548
CC License:  CC Attribution-Noncommercial-No Derivative Works 2.5 India
ISSN: 0975-0967 (Online); 0972-5849 (Print)
Source:IJBT Vol.02(4) [October 2003]

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