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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
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Research Journals >
Indian Journal of Biotechnology (IJBT) >
IJBT Vol.02 [2003] >
IJBT Vol.02(4) [October 2003] >
| Title: | Induced Immunity against Haemolymph Proteins of Anopheles stephensi: Effects on Fecundity and Transmission Blocking of Malaria Parasite |
| Authors: | Gulia, Monika
Gakhar, S K |
| Keywords: | Anopheles
Haemolymph
Antibodies
Parasite
Transmission-blocking |
| Issue Date: | Oct-2003 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Rabbit
antibodies to nine antigens (100, 88, 80, 64, 55, 43, 29, 23 and 15 kDa),'
derived from haemolymph of
Anopheles
stephensi mosquitoes after first gonotrophic cycle, tended to reduce the
number of eggs produced by the
mosquitoes
and block the transmission of malaria parasite, Plasmodium vivax. Cross-reactivity
of these antibodies
was
checked both by Western blotting and in vivo ELISA. In addition, effect
of these antibodies on mortality,
engorgement
and hatchability in mosquitoes was also determined. The results indicated that
haemolymph antibodies
have
the potential to disrupt the reproductive physiology of mosquitoes and further
studies are needed with the
target antigens. |
| Page(s): | 543-548 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0967 (Online); 0972-5849 (Print) |
| Source: | IJBT Vol.02(4) [October 2003]
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