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Title: Emergence of Antibiotic Resistance in Nosocomial Strains of Coagulase Negative Staphylococci (CNS)
Authors: Geetha, M S
Ashok, C
Sullia, S B
Keywords: Coagulase Negative Staphylococci (CNS);Antibiotic resistance;Plasmid DNA
Issue Date: Oct-2003
Publisher: NISCAIR-CSIR, India
Abstract: Nosocomial infections caused by Coagulase Negative Staphylococci (CNS) have reached epidemic proportions. In the present work, about 26 clinically significant CNS belonging to Staphylococcus epidermidis and S. saprophyticus, were isolated from various clinical specimens and hospital environments. A few CNS strains have shown multiple antibiotic resistance to ampicillin, cotrimoxazole, cephalexin, cefotaxime, penicillin, tetracycline, gentamicin and lincomycin. Plasmid analysis of representative clinical isolates demonstrated the presence of 2-29.9 kb sized plasmid DNA. Intra and inter-specific gene transfer was observed between different species of CNS and S. aureus which suggests the rapid emergence of multiple antibiotic resistance in CNS.
Page(s): 499-503
ISSN: 0975-0967 (Online); 0972-5849 (Print)
Appears in Collections:IJBT Vol.02(4) [October 2003]

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