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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Biotechnology (IJBT) >
IJBT Vol.02 [2003] >
IJBT Vol.02(3) [July 2003] >
| Title: | Phytoestrogens |
| Authors: | Sebastian, K S
Thampan, Raghava Varman |
| Keywords: | Phytoestrogens
Estrogen receptor 
Non-activated estrogen receptor
Nuclear estrogen receptor II
Estrogen receptor activation factor |
| Issue Date: | Jul-2003 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Phytoestrogens are chemical agents, originated
from plants, which display structural and functional similarity to
17 estradiol and show both estrogen agonist and antagonistic properties.
During recent years phytoestrogens attracted immense public attention as an
alternative to estradiol in estrogen replacement therapy for treating
postmenopausal women. Epidemiological data have shown a strong correlation
between the incidence of hormone dependent diseases and the nature of the diet.
Different phytoestrogens exert their biological effects through different mechanisms
and through different types of receptors, the expression of which appears to be
tissue specific. Though there is considerable amount of epidemiological data
indicating the possible health benefits of phytoestrogens, for better
utilization of these agents a deeper understanding of the mechanism of action
of these estrogens is essential. This will help in the identification of a
particular type of phytoestrogen, which can elicit a tissue specific effect
under a given clinical condition. |
| Page(s): | 387-395 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0967 (Online); 0972-5849 (Print) |
| Source: | IJBT Vol.02(3) [July 2003]
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