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Indian Journal of Biotechnology (IJBT) >
IJBT Vol.02 [2003] >
IJBT Vol.02(2) [April 2003] >
| Title: | Bioinformatics: Advancing Biotechnology through Information Technology Part II: In silico Gene Prediction |
| Authors: | Adak, Sudeshna |
| Keywords: | Homology
Ab initio
Synteny
EST
Genome annotation |
| Issue Date: | Apr-2003 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | The
paper reviews computational tools and algorithms for in silico genome
annotation and, in particular, the
Bioinformatics
resources available for in silico gene prediction. Gene prediction
requires a combination of
algorithms
with different types of biological databases and the author intends to provide
the biologist or
biotechnology
researcher an insight into the use of these methods. The explosion of information
seen in molecular
biology
has created a veritable maze, through which careful navigation is required for
research and innovation in
biotechnology.
Online databases have given scientists and researchers across the world access
to unimaginable
volumes
of biologically relevant data. Bioinformatics, a truly multidisciplinary
science, aims to bring the benefits of
computer
technologies to bear in understanding the biology of life itself. In this
second paper of a three part series,
the
tremendous value of gene prediction algorithms is discussed, in the context of
transforming raw biological
sequence
data into biologically useful knowledge. It is the first step in harnessing the
biological data arising out of the
genome projects into a new and improved understanding
of biology of organisms. |
| Page(s): | 159-174 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0967 (Online); 0972-5849 (Print) |
| Source: | IJBT Vol.02(2) [April 2003]
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