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Indian Journal of Chemistry -Section A (IJC-A) >
IJC-A Vol.50A [2011] >
IJC-A Vol.50A(03-04) [March-April 2011] >
| Title: | Bacterial model systems for cytochrome c oxidase biogenesis |
| Authors: | Hannappel, A
Bundschuh, F A
Greiner, P
Alles, M
Werner, C
Richter, O M
Ludwig, B |
| Keywords: | Bioinorganic chemistry
Biogenesis
Oxidase assembly
Terminal oxidase
Heme copper oxidase
Chaperone proteins
Heme a
Surf1
CbaX
CtaG
Cox11
Sco |
| Issue Date: | Mar-2011 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Cytochrome c oxidase is the key player in cellular
respiration, catalysing the reduction of molecular oxygen to water via its internal heme and copper
redox centres. Biogenesis of the enzyme is a complex process involving up to 30
accessory proteins in higher eukaryotes. Factors directly involved in cofactor
recruitment and insertion into the two core structural subunits I and II are
also present in many bacteria and have been conserved during evolution. Herein
we briefly review the chaperones required during early biogenesis steps, with
special emphasis on the bacterial counterparts. |
| Page(s): | 374-382 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0975(Online); 0376-4710(Print) |
| Source: | IJC-A Vol.50A(03-04) [March-April 2011]
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