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IJC-B Vol.50B(03) [March 2011] >


Title: Zinc(II) chloride catalysed one pot synthesis of some new 4-thiazolidinone derivatives as biologically potent agents
Authors: Shah, Pushpak M
Patel, Manish P
Keywords: Zinc chloride
2-chloro-3-formyl quinoline
Amino benzothiazole
Thioglycolic/thiolactic acid
Issue Date: Mar-2011
Publisher: NISCAIR-CSIR, India
Abstract: Thiazolidin-4-ones 3a-l, 4a-l have been synthesized by the cyclocondensation of thioglycolic acid/thiolactic acid, 2-amino benzothiazoles 2a-d and 2-chloro-3-formyl quinolines 1a-c in the presence of ZnCl2. The structure of the compounds 3a-l, 4a-l have been confirmed from 1H NMR, 13C NMR, FT-IR spectroscopy and elemental analysis. All the compounds have been screened for their antimicrobial and antifungal activity against several microbes.
Page(s): 310-314
CC License:  CC Attribution-Noncommercial-No Derivative Works 2.5 India
ISSN: 0975-0983(Online); 0376-4699(Print)
Source:IJC-B Vol.50B(03) [March 2011]

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