Please use this identifier to cite or link to this item:
|Title:||Synthesis and biological evaluation of pyrido(2, 3-<i style="">d</i>)pyrimidine-carboxylate derivatives|
Aanandini, M Vijey
Kumar, M Sathish
Sateesh, J N
|Abstract:||Ethyl-5-amino-8-(4-halophenyl)-2-methyl-4,7-dioxo-3,4,5,6,7,8-hexahydro pyrido(2,3-<i style="">d</i>) pyrimidine-6-carboxylate and ethyl-5-amino-8-(4-halophenyl)-2-amino-4,7 dioxo-3,4,5,6,7,8 hexahydropyrido(2,3-<i style="">d</i>)pyrimidine-6-carboxylate derivatives have been synthesized through nucleophilic substitution reactions with the use of amidines, followed by 4-haloanilines and malonic acid. These synthesized novel derivatives have been confirmed by elemental analysis, IR, <sup>1</sup>H NMR and mass spectra. These novel derivatives have also been screened for antibacterial, antifungal and antitumor activity.|
|Appears in Collections:||IJC-B Vol.50B(03) [March 2011]|
Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.